Our Research

All of our projects depend on the creation and advancement of direct infusion of drugs and therapies into the brain. We have developed a technique in which nanoparticles, including viral vectors and liposomes can be infused directly into brain tumors to give enhanced drug efficacy. For many years, and continuing still, we have been working on development of direct drug delivery into the brain including cell transplantation, gene transfer and growth factor infusions for Parkinson's disease. Through gene therapy, we are working to eliminate the gene responsible for Niemann-Pick (acid sphingomyelinase). By studying the effects of L-Dopa on the brain, we are developing gene therapy for L-Dopa-induced dyskinesia.