UCSF Neurological Surgery faculty since 2001
 
Read about Dr. Liu's current research
 
Dr. Liu's research focuses on determining the mechanisms mediating functional recovery and endogenous neural-stem-cell plasticity following cerebral ischemia an traumatic brain injury. This work is funded by the National Institutes of Health (NIH), the Department of Defense, the Department of Veterans Affairs, and the American Heart Association. The Liu laboratory is engaged in molecular and neurobehavioral research to study cell death and regeneration events after stroke, head trauma, and hypoglycemic brain injuries.
 
Education, Training, and Previous Positions
 
1984: BS, National Taiwan University, Taipei, Taiwan
1992: PhD, Boston University Medical Center, Boston, MA
1992- 1996: Postdoctoral fellow, Neurology, UCSF
1996- 1998: Postgraduate researcher, Neurology, UCSF
1998- 1999: Assistant researcher, Neurology, UCSF
1999- 2001: Assistant Researcher, Neurological Surgery, UCSF and NCIRE
2001: Assistant Professor, Neurological Surgery, UCSF
2005: Associate Adjunct Professor, Neurological Surgery UCSF
 
Selected Professional Memberships and Appointments
 
NIH, National Institute of Neurological Disorders, Brain Disorders and Clinical Neuroscience, and American Heart Association Study Section
Editorial Board, Stroke
Society for Neuroscience
American Heart Association
American Association for the Advancement of Science
American Society of Cell Biology
 
Contact
 
Jialing Liu PhD
University of California, San Francisco
Department of Neurological Surgery
Box 0520
San Francisco, CA 94143-0520
Phone:(415) 221-4810 x2987
Fax: (415)379-5593
E-mail: jialing.liu@ucsf.edu
 
Selected Recent Publications
 
Liu Z, Fan Y, Won SJ, Neumann M, Hu D, Zhou L, Weinstein PR, Liu J. Chronic treatment with minocycline preserves adult new neurons and reduces functional impairment after focal cerebral ischemia. Stroke 2007;38(1):146-52.
 
Fan Y, Liu Z, Weinstein PR, Fike JR, Liu J. Environmental enrichment enhances neurogenesis and improves functional outcome after cranial irradiation. Eur J Neurosci 2007;25(1):38-46.
 
Hong SM, Liu Z, Fan Y, Neumann M, Won SJ, Lac D, Lum X, Weinstein PR, Liu J. Reduced hippocampal neurogenesis and skill reaching performance in adult Emx1 mutant mice. Exp Neurol 2007;206(1):24-32.
 
Matsumori Y, Northington FJ, Hong SM, Kayama T, Sheldon RA, Vexler ZS, Ferriero DM, Weinstein PR, Liu J. Reduction of caspase-8 and -9 cleavage is associated with increased c-FLIP and increased binding of Apaf-1 and Hsp70 after neonatal hypoxic/ischemic injury in mice overexpressing Hsp70. Stroke 2006;37(2):507-12.
 
Matsumori Y, Hong SM, Fan Y, Kayama T, Hsu CY, Weinstein PR, Liu J. Enriched environment and spatial learning enhance hippocampal neurogenesis and salvages ischemic penumbra after focal cerebral ischemia. Neurobiol Dis 2006;22(1):187-98.
 
Aoyama K, Suh SW, Hamby AM, Liu J, Chan WY, Chen Y, Swanson RA. Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse. Nat Neurosci 2006;9(1):119-26.
 
Suh SW, Fan Y, Hong SM, Liu Z, Matsumori Y, Weinstein PR, Swanson RA, Liu J. Hypoglycemia induces transient neurogenesis and subsequent progenitor cell loss in the rat hippocampus. Diabetes 2005;54(2):500-9.
 
Yenari MA, Liu J, Zheng Z, Vexler ZS, Lee JE, Giffard RG. Antiapoptotic and anti-inflammatory mechanisms of heat-shock protein protection [Review]. Ann N Y Acad Sci 2005;1053:74-83.
 
Matsumori Y, Hong SM, Aoyama K, Fan Y, Kayama T, Sheldon RA, Vexler ZS, Ferriero DM, Weinstein PR, Liu J. Hsp70 overexpression sequesters AIF and reduces neonatal hypoxic/ischemic brain injury. J Cereb Blood Flow Metab 2005; 25(7):899-910.
 
Raber J, Fan Y, Matsumori Y, Liu Z, Weinstein PR, Fike JR, Liu J. Irradiation attenuates neurogenesis and exacerbates ischemia-induced deficits. Ann Neurol 2004;55(3):381-9.
 
Schmitt-Ulms G, Hansen K, Liu J, Cowdrey C, Yang J, DeArmond SJ, Cohen FE, Prusiner SB, Baldwin MA. Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues. Nat Biotechnol 2004;22(6):724-31.
 
Suh SW, Aoyama K, Chen Y, Garnier P, Matsumori Y, Gum E, Liu J, Swanson RA. Hypoglycemic neuronal death and cognitive impairment are prevented by poly(ADP-ribose) polymerase inhibitors administered after hypoglycemia. J Neurosci 2003;23(33):10681-90.